Selected Publications
*equal contribution
**co-corresponding
- Plenge, P., Yang, D., Salomon, K., Laursen, L., Kalenderoglou, I.E., Newman, A.H., Gouaux, E., Coleman, J.A.**, Loland, C.J. (2021). The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. Nat. Comm., 12, 5063.
- Coleman, J.A.*, Navratna, V.*, Antermite D., Yang, D, Bull, J.A., Gouaux, E. (2020). Chemical and structural investigation of the paroxetine-human serotonin transporter complex. eLife, 9:e56427.
- Coleman, J.A.*, Yang, D.*, Zhao, Z., Wen, P., Yoshioka, C., Tajkhorshid, E., Gouaux, E. (2019). Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport. Nature 569, 141-145.
- Coleman, J. A., Gouaux, E. (2018). Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol. 25, 170-175.
- Coleman, J. A., Green, E. M., Gouaux, E. (2016). Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram. J. Vis. Exp., e54792, doi:10.3791/54792.
- Coleman J.A., Green E.M., Gouaux E. (2016). X-ray structures and mechanism of the human serotonin transporter. Nature 532 (7599), 334-339.
- Green E.M., Coleman J.A., Gouaux E. (2015). Thermostabilization of the human serotonin transporter in an antidepressant-bound conformation. PloS One 10 (12), e0145688.
- Vestergaard A.L., Coleman J.A., Lemmin T., Mikkelsen S.A., Molday L.L., Vilsen B., Molday R.S., Dal Peraro M., Peter Andersen J. (2014). Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2. Proc. Natl. Acad. Sci. 111 (14), E1334-E1343.
- Coleman J.A.*, Zhu X.*, Djajadi H.R., Molday L.L, Smith R.S., Libby R.T., John S.W.M., Molday R.S. (2014). Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival. J. Cell. Sci. 127 (5), 1138-1149.
- Coleman J.A., Quazi F., Molday R.S. (2013). Mammalian P(4)-ATPases and ABC transporters and their role in phospholipid transport. Biochim. Biophys. Acta. 1831, 555-74.
- Coleman J.A., Vestergaard A.L., Molday R.S., Vilsen B., Peter Andersen J. (2012). Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2. Proc. Natl. Acad. Sci. 109, 1449-54.
- Coleman J.A., Molday RS. (2011). Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2. J. Biol. Chem. 286, 17205-16.
- Coleman J.A., Kwok M.C., Molday R.S. (2009). Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes. J. Biol. Chem. 284, 32670-9.